Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	D516del	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB DNA-directed RNA polymerase subunit beta	D516T	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D516V	A1549T GAC-GTC A1548T GAT->GTT	-	Mycobacterium tuberculosis, Escherichia coli, Mycobacterium smegmatis, Rhodococcus equi, Mycobacterium gastri	rifampicinrifabutinrifampicin\|ethambutol+1 more	Reslit	Supported
rpoB RNA polymerase beta subunit	D516Y	GAC-TAC GAT->TAT	-	Mycobacterium tuberculosis, Escherichia coli	rifampicinrifabutin	Reslit	Supported
rpoB β-subunit of RNA polymerase	D521A	-	-	Pseudomonas fluorescens	rifampicin	Reslit	Candidate
rpoB RNA polymerase β-chain	D521G	G1562G	-	Pseudomonas aeruginosa, Pseudomonas fluorescens	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	D521N	G1561A	-	Pseudomonas aeruginosa	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D523E	-	-	Mycobacterium abscessus	rifampicin\|rifabutin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D526G	-	-	Brucella melitensis, Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase subunit beta	D526N	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate