Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	H486Y	-	upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic, DNA-directed RNA polymerase subunit beta RpoB	Enterococcus faecium	rifampicindaptomycindaptomycin\|rifaximin	Reference Gene CatalogReslit	Confirmed
rpoB RNA polymerase beta subunit	H487D	-	-	Lactobacillus rhamnosus	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H490Y	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H491D	-	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H491N	C1472T	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H491R	-	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H491Y	-	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	H499L	-	-	Streptococcus pneumoniae	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H499R	-	-	Streptococcus pneumoniae	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	H499Y	-	-	Streptococcus pneumoniae, Mycobacterium tuberculosis	rifampicin	Reslit	Candidate