Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase subunit	I517M	-	-	Chlamydia trachomatis	rifampicin	Reslit	Supported
rpoB	I527F	-	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder Database	Confirmed
rpoB RNA polymerase beta-subunit	I527L	-	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	I527M	C1583G C1582G A1580G	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus epidermidis, Staphylococcus aureus	rifampicinrifampicin\|vancomycinrifampicin\|teicoplanin\|vancomycin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	I527P	A1580C	-	Staphylococcus aureus	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	I528F	-	-	Listeria monocytogenes	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	I528V	A1582G	-	Bacillus subtilis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	I545L	-	-	Streptococcus pneumoniae	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	I545N	-	-	Streptococcus pneumoniae	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	I548M	C1644G	multiple resistance variants	Clostridium difficile, Clostridioides difficile, Clostridium ljungdahlii	rifampicin\|rifaximinrifampicin	Card DatabaseReslit	Confirmed