Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	Q458L	-	-	Chlamydia trachomatis	rifampicin	Reslit	Candidate
rpoB	Q465K	-	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder Database	Confirmed
rpoB	Q465R	-	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Card DatabaseReference Gene CatalogResFinder Database	Confirmed
rpoB	Q468I	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene Catalog	Established
rpoB RNA polymerase beta subunit	Q468K	C1403A C1404A	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus epidermidis, Staphylococcus aureus	rifampicinrifampicin\|vancomycin\|daptomycin	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q468L	-	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus epidermidis, Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q468R	C1403G	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q469K	-	single resistance variant	Staphylococcus epidermidis, Bacillus subtilis	rifampicin	Card DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q469L	-	-	Staphylococcus epidermidis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q469R	-	single resistance variant	Staphylococcus epidermidis, Bacillus subtilis	rifampicincefotaxime	Card DatabaseReslit	Confirmed