Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	Q472R	-	The Q472R mutation in rpoB confers rifampicin resistance in B. velezensis.	Bacillus velezensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q473K	-	-	Enterococcus faecium	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q473L	-	upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic	Enterococcus faecium	daptomycin	Reslit	Candidate
rpoB DNA-directed RNA polymerase beta chain	Q474R	-	-	Flavobacterium psychrophilum	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	Q486L	-	-	Streptococcus pneumoniae, Staphylococcus aureus	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q486R	-	-	Staphylococcus aureus	rifampicin	Reslit	Candidate
rpoB DNA-directed RNA polymerase beta subunit	Q489K	-	-	Clostridium difficile	rifampicin\|rifaximinrifampicin	Reslit	Candidate
rpoB	Q489L	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	rifaximin	Reference Gene Catalog	Established
rpoB β-subunit of RNA polymerase	Q490P	-	-	Salmonella enterica	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta-subunit	Q490R	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate