Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	R529S	-	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Escherichia coli, Shigella sonnei	rifampicinrifamycins	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	R533P	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R539S	-	-	Brucella melitensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R544H	-	-	Legionella pneumophila	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R548H	-	increased MIC for rifampin	Mycobacterium tuberculosis, Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB DNA-directed RNA polymerase beta subunit	R552C	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	R552H	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R552L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R637A	-	-	Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB	R644H	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	beta lactams	Reference Gene Catalog	Established