Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	R687H	-	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Escherichia coli, Shigella sonnei	rifampicinrifamycins	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB Beta-subunit of RNA polymerase	R701H	-	single resistance variant	Helicobacter pylori	rifampicin\|rifabutinrifampicin	Card DatabaseReslit	Confirmed
rpoB beta-subunit of RNA polymerase	R827C	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB	R827H	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB DNA-directed RNA polymerase beta subunit RpoB	R917C	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S105T	-	-	Mycobacterium tuberculosis	isoniazid	Reslit	Candidate
rpoB RNA polymerase beta-subunit	S135L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S175F	C526T	-	Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	S177L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB subunit β of the RNA polymerase (RNAP)	S186F	TCT->TTC	-	Pseudomonas aeruginosa	ceftazidime	Reslit	Candidate