Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta-subunit	S433L	-	-	Streptomyces coelicolor	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S435L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB beta subunit of RNA polymerase holoenzyme	S437L	-	-	Mycobacterium leprae	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S437Q	-	-	Mycobacterium leprae	rifampicin	Reslit	Candidate
rpoB DNA-directed RNA polymerase subunit beta	S438L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S441A	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseReslit	Confirmed
rpoB	S441K	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	S441L	AGC->CTC	single resistance variant, multiple resistance variants	Mycobacterium tuberculosis, Mycobacterium smegmatis, Mycobacterium bovis	capreomycinrifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB	S441M	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	S441Q	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed