Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
dacB	L204P	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
dacB	L402P	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
dacB	N317H	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	aztreonam\|ceftazidime avibactam\|cephalosporins	Reference Gene Catalog	Established
dacB penicillin-binding protein	S230I	-	-	-	ceftazidime\|cefepime\|piperacillin\|tazobactam\|piperacillin tazobactam	Reslit	Candidate
dacB penicillin-binding protein	T27S	-	-	-	ceftazidime\|cefepime\|piperacillin\|tazobactam\|piperacillin tazobactam	Reslit	Candidate
dacB nonessential low molecular mass PBP4	T428P	-	inactivation, D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	ceftazidimecephalosporins	Reference Gene CatalogReslit	Confirmed
dacB nonessential low molecular mass PBP4	T79P	-	inactivation	Pseudomonas aeruginosa	ceftazidime\|cefepime\|piperacillin\|imipenem	Reslit	Candidate
dacB nonessential low molecular mass PBP4	W273X	-	inactivation	Pseudomonas aeruginosa	ceftazidime\|cefepime\|piperacillin\|imipenem	Reslit	Candidate
dacB penicillin-binding protein PBP4	W388L	-	-	Pseudomonas aeruginosa	ceftazidime avibactam	Reslit	Candidate
dacB	W459Ter	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established