Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
dacB	W92R	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
dacS two-component system histidine kinase	E238D	-	two-component sensor histidine kinase DacS	Clostridioides difficile	vancomycin	Reference Gene CatalogReslit	Confirmed
dacS two-component system histidine kinase	L183P	-	-	Clostridioides difficile	vancomycin	Reslit	Candidate
dacS two-component system histidine kinase	V183A	-	two-component sensor histidine kinase DacS	Clostridioides difficile	vancomycin	Reference Gene CatalogReslit	Confirmed
dacS two-component system histidine kinase	V238M	-	-	Clostridioides difficile	vancomycin	Reslit	Candidate
dagK diacylglycerol kinase	-	G245A	-	Listeria monocytogenes	benzalkonium chloride	Reslit	Candidate
dagK diacylglycerol kinase	P226A	-	-	Enterococcus faecium	daptomycin	Reslit	Candidate
dat d-amino acid aminotransferase	S180F	-	-	-	beta lactams	Reslit	Candidate
ddl d-Ala:d-Ala ligase	E13G	-	-	-	vancomycin	Reslit	Candidate
ddl6 D-alanine-D-alanine ligase	W259C	G777T	The mutation at c.777 (G>T) leads to a Trp259Cys substitution, which increases the MIC of D-cycloserine by fourfold.	Escherichia coli, Treponema denticola	cycloserine	Reslit	Candidate