Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase A	S84Y	-	single resistance variant, DNA gyrase subunit A GyrA	Staphylococcus epidermidis, Streptococcus pneumoniae, Haemophilus parainfluenzae, Haemophilus influenzae	ciprofloxacin\|ofloxacin\|gatifloxacin\|moxifloxacinciprofloxacin\|sparfloxacin\|grepafloxacin\|moxifloxacindelafloxacin+2 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA	S85A	-	DNA gyrase subunit A GyrA	Staphylococcus pseudintermedius	quinolones	Reference Gene Catalog	Established
gyrA DNA gyrase subunit A	S85F	-	-	Vibrio cholerae, Escherichia coli	ciprofloxacin\|nalidixic acidciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S85L	-	reduced susceptibility to fluoroquinolones	Bacillus anthracis, E. coli	ciprofloxacin\|moxifloxacinciprofloxacinfluoroquinolones	Reslit	Supported
gyrA DNA gyrase subunit A	S85P	-	Target modification, single resistance variant, DNA gyrase subunit A GyrA	Staphylococcus aureus	ciprofloxacinlevofloxacinfluoroquinolones+2 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	S864P	-	-	Salmonella enterica	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	S86L	C257T	-	Campylobacter jejuni, Campylobacter coli, Campylobacter spp.	quinolonesciprofloxacin\|nalidixic acidfluoroquinolones+1 more	Reslit	Supported
gyrA DNA gyrase subunit A	S87A	AGC->GCC	-	Corynebacterium provencense	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S87F	-	confers resistance	Corynebacterium striatum, Staphylococcus aureus, Campylobacter jejuni, Corynebacterium spp., Salmonella enterica	ciprofloxacin\|levofloxacinfluoroquinolonesciprofloxacin+1 more	Reslit	Supported
gyrA DNA gyrase subunit A	S87G	-	-	Escherichia coli	ciprofloxacin\|norfloxacin	Reslit	Candidate