Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB DNA gyrase subunit B	D461N	G1381A A1383G	single resistance variant	Mycobacterium tuberculosis	fluoroquinolonesofloxacin\|moxifloxacin\|ciprofloxacin\|levofloxacinofloxacin\|moxifloxacin\|ciprofloxacin+4 more	Card DatabaseResFinder DatabaseReslit	Confirmed
gyrB DNA gyrase B subunit	D464N	GAT->AAT	single resistance variant	Mycobacterium leprae	ofloxacin\|moxifloxacin\|sitafloxacin\|ciprofloxacin\|levofloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	D465N	G1394A	-	Clostridioides difficile	levofloxacin\|ciprofloxacinfluoroquinolones	Reslit	Candidate
gyrB	D465Y	-	single resistance variant	Clostridium ljungdahlii	fluoroquinolones	Card Database	Established
gyrB DNA gyrase subunit B	D468N	-	-	Clostridioides difficile	fluoroquinolones	Reslit	Candidate
gyrB DNA gyrase subunit B	D472A	-	-	-	fluoroquinolonesofloxacin\|moxifloxacin\|ciprofloxacin\|levofloxacin	Reslit	Candidate
gyrB fluoroquinolone resistance	D472G	-	-	Mycobacterium tuberculosis	ciprofloxacin\|fluoroquinolones\|levofloxacin\|moxifloxacin\|ofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	D472H	-	-	Mycobacterium tuberculosis	fluoroquinolonesofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	D472N	-	-	Mycobacterium tuberculosis	ofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	D472V	-	-	Mycobacterium tuberculosis	ofloxacin	Reslit	Candidate