Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB DNA gyrase subunit B | D435E | - | - | Streptococcus pneumoniae | ciprofloxacinofloxacin|levofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D435G | - | - | Streptococcus pneumoniae | levofloxacin|sparfloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D435N | - | - | Helicobacter pylori | levofloxacin | Reslit | Candidate |
| D436N | - | DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Staphylococcus aureus | quinolones | Reference Gene Catalog | Established | |
gyrB DNA gyrase subunit B | D437E | - | - | Staphylococcus aureus | nemonoxacin|moxifloxacin|levofloxacin|ciprofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D443A | - | - | - | levofloxacin|moxifloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D443N | - | - | - | levofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D460G | - | - | fluoroquinolones | Reslit | Candidate | |
| D461A | - | - | Mycobacterium tuberculosis | fluoroquinolones | ResFinder Database | Established | |
gyrB DNA gyrase subunit B | D461H | - | single resistance variant | Mycobacterium tuberculosis | fluoroquinolonesofloxacin|moxifloxacin|ciprofloxacin|levofloxacinofloxacin|moxifloxacin|ciprofloxacin+3 more | Card DatabaseResFinder DatabaseReslit | Confirmed |
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