Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB DNA gyrase subunit B	R304W	-	-	-	levofloxacin	Reslit	Candidate
gyrB	R377G	-	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium ljungdahlii, Clostridioides difficile	fluoroquinolonesquinolones	Card DatabaseReference Gene Catalog	Confirmed
gyrB DNA gyrase subunit B	R379L	-	-	Streptococcus pneumoniae	fluoroquinolones	Reslit	Candidate
gyrB	R389P	-	single resistance variant	Clostridium ljungdahlii	fluoroquinolones	Card Database	Established
gyrB DNA gyrase subunit B	R421H	-	-	-	ofloxacin\|moxifloxacin\|ciprofloxacin\|levofloxacin	Reslit	Candidate
gyrB	R438L	-	Target modification, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Salmonella enterica	nalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrB DNA gyrase subunit B	R445S	-	-	Streptococcus pneumoniae	clinafloxacin\|ciprofloxacin\|trovafloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	R446C	-	-	Mycobacterium tuberculosis	ofloxacin\|moxifloxacin\|ciprofloxacin\|levofloxacinlevofloxacin\|moxifloxacinfluoroquinolones	ResFinder DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	R446H	G1338A	-	Mycobacterium tuberculosis	levofloxacinfluoroquinolones	ResFinder DatabaseReslit	Confirmed
gyrB	R446L	-	-	Mycobacterium tuberculosis	fluoroquinolones	ResFinder Database	Established