Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB DNA gyrase subunit B	S361P	-	-	E. coli	ciprofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S366A	TCA->GCC	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium ljungdahlii, Clostridioides difficile	fluoroquinolonesquinolones	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S366V	-	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium difficile, Clostridium ljungdahlii, Clostridioides difficile	fluoroquinolonesciprofloxacin\|moxifloxacinquinolones	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S416A	-	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium difficile, Clostridium ljungdahlii, Clostridioides difficile	moxifloxacin\|ciprofloxacin\|gatifloxacin\|levofloxacinmoxifloxacinciprofloxacin+3 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S416Y	C1247A	-	Mycoplasma synoviae	fluoroquinolones	Reslit	Candidate
gyrB DNA gyrase subunit B	S417N	-	-	Mycoplasma synoviae	enrofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S426G	-	-	Salmonella Typhi, Salmonella Paratyphi	ciprofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S429T	-	-	Helicobacter pylori	fluoroquinolones	Reslit	Candidate
gyrB DNA gyrase B subunit	S431P	-	-	Salmonella enterica	nalidixic acid	Reslit	Candidate
gyrB DNA gyrase subunit B	S447F	-	single resistance variant	Mycobacterium tuberculosis	fluoroquinolonesofloxacin	Card DatabaseResFinder DatabaseReslit	Confirmed