Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB DNA gyrase subunit B	S447P	G1341A	-	-	levofloxacinlevofloxacin\|moxifloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S463A	-	single resistance variant	Morganella morganii, Salmonella Typhimurium, Salmonella Enteritidis	quinolonesciprofloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	S464F	-	reduced susceptibility to ciprofloxacin, Target modification, single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Salmonella enterica, Salmonella Typhimurium, Salmonella Enteritidis, Escherichia coli, Pseudomonas aeruginosa, Salmonella Typhi	ciprofloxacinfluoroquinolonesciprofloxacin\|nalidixic acid+4 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	S464T	-	Target modification, single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Salmonella Gallinarum, Salmonella enterica, Clostridium ljungdahlii	ciprofloxacinfluoroquinolonesquinolones	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	S464Y	-	Target modification, single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Proteus mirabilis, E. coli, Morganella morganii	ciprofloxacinlevofloxacinkanamycin+3 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	S465F	-	-	Francisella tularensis	ciprofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S465Y	-	-	Francisella novicida, Francisella tularensis, Pseudomonas aeruginosa	ciprofloxacin	Reslit	Candidate
gyrB DNA gyrase B subunit	S466F	-	DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Pseudomonas aeruginosa, Escherichia coli	ciprofloxacinfluoroquinolonesciprofloxacin\|levofloxacin+3 more	Reference Gene CatalogReslit	Confirmed
gyrB DNA gyrase B subunit	S466Y	TCA->TAC	DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Pseudomonas aeruginosa	ciprofloxacinfluoroquinolonesquinolones	Reference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S467F	-	-	Pasteurella multocida, Pseudomonas aeruginosa	fluoroquinolonesciprofloxacin	Reslit	Candidate