Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
macA Membrane fusion protein | - | reduces resistance to macrolides in vivo | Escherichia coli | macrolides | Reslit | Candidate | |
macA periplasmic membrane fusion protein | G353A | - | disrupts the proper assembly of the MacA-MacB complex | Escherichia coli | erythromycin|oleandomycin | Reslit | Candidate |
macA periplasmic membrane fusion protein | G357A | - | modest effect on the MP domain of MacA | Escherichia coli | erythromycin|oleandomycin | Reslit | Candidate |
| - | efflux pump MacAB promoter region | Neisseria gonorrhoeae | azithromycin | Reference Gene Catalog | Established | ||
marA efflux pump regulator | S103G | - | - | Escherichia coli, Klebsiella pneumoniae | tigecycline | Reslit | Candidate |
marA global activator of the AcrAB-TolC efflux pump | S127N | - | - | Escherichia coli | fluoroquinolones | Reslit | Candidate |
marB efflux pump regulator | H44Q | - | - | Escherichia coli | minocycline|meropenem|aztreonam | Reslit | Candidate |
marB transcriptional activator | L27P | - | Escherichia coli | tigecycline | Reslit | Candidate | |
marR transcriptional regulator | - | - | Escherichia coli | norfloxacin | Reslit | Candidate | |
| - | - | Salmonella enterica | ciprofloxacin | Reslit | Candidate |
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