Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mexR transcriptional repressor of the mexAB-oprM efflux pump	-	C3T	interferes with the regular transcription of the efflux component MexA	Pseudomonas aeruginosa	carbenicillin\|cef\|ciprofloxacin	Reslit	Candidate
mexR transcriptional repressor of the MexAB-OprM efflux pump	-	G212A	-	Pseudomonas aeruginosa	carbapenems\|cephalosporins\|fluoroquinolones	Reslit	Candidate
mexR transcriptional regulator	A110T	-	reduced expression	Pseudomonas aeruginosa	ceftazidime\|cefepime\|ticarcillin\|imipenem	Reslit	Candidate
mexR efflux pump regulator	A156T	-	-	Pseudomonas aeruginosa	fluoroquinolones	Reslit	Candidate
mexR transcriptional regulator of MarR family	A164C	-	inactivating the OprD porin within the cellular membrane	Pseudomonas aeruginosa	meropenem	Reslit	Candidate
mexR transcriptional repressor of MexEF efflux pump	A166V	-	mutations in mexR have resulted in loss of repressor activity (i.e., higher expression levels of mexAB)	Shewanella oneidensis	ciprofloxacin	Reslit	Candidate
mexR	C138A	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
mexR	C138G	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
mexR transcriptional repressor	C62S	-	-	Pseudomonas aeruginosa	norfloxacin	Reslit	Candidate
mexR	C62Ter	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established