Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mexR negative regulator of the MexAB-OprM efflux pump	D89E	-	-	Pseudomonas aeruginosa	cefiderocol	Reslit	Candidate
mexR	D89N	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexR	E109Ter	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexR	E126V	-	-	Pseudomonas aeruginosa	ciprofloxacin\|levofloxacin	Reslit	Candidate
mexR efflux regulator	E41K	-	-	Pseudomonas aeruginosa	ciprofloxacin\|tetracycline\|phenicols\|trimethoprim	Reslit	Candidate
mexR	G101E	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexR multidrug resistance operon repressor	G155D	-	mutations in mexR ... cause upregulation of the efflux pumps and being associated with β-lactam resistance	Pseudomonas aeruginosa	meropenem	Reslit	Candidate
mexR transcriptional regulator of the mexAB-oprM efflux system	G531D	-	-	Pseudomonas aeruginosa	aztreonam	Reslit	Candidate
mexR Transcriptional regulator of mexAB-oprM	G71E	-	-	Pseudomonas aeruginosa	aminoglycosides\|fluoroquinolones\|macrolides	Reslit	Candidate
mexR transcriptional repressor	H107P	-	-	Pseudomonas aeruginosa	aztreonam\|ciprofloxacinfluoroquinolonesticarcillin\|cefepime\|aztreonam	Reslit	Supported