Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mexR	Q49Ter	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexR transcriptional regulator of MarR family	Q55P	-	increased MexAB efflux pump genes expression by altering MexR’s binding capacity	Pseudomonas aeruginosa	meropenem	Reslit	Candidate
mexR	Q94Ter	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexR MarR family transcriptional regulator	R70Q	G209A	prevents MexR from binding to the intergenic region between mexR and mexAB-oprM operon, effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonamaztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene CatalogReslit	Confirmed
mexR repressor of the mexR-mexA-mexB-oprM operon	R83C	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam\|ofloxacinaztreonam\|carbenicillin\|piperacillin tazobactam\|meropenemaztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene CatalogReslit	Confirmed
mexR repressor of the mexR-mexA-mexB-oprM operon	R91C	-	-	Pseudomonas aeruginosa	aztreonam\|ofloxacin	Reslit	Candidate
mexR repressor of the mexR-mexA-mexB-oprM operon	R91H	-	-	Pseudomonas aeruginosa	aztreonam\|ofloxacin	Reslit	Candidate
mexR Transcriptional regulator of mexAB-oprM	S209R	-	-	Pseudomonas aeruginosa	aminoglycosides\|fluoroquinolones\|macrolides	Reslit	Candidate
mexR	T130P	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexR repressor of the mexR-mexA-mexB-oprM operon	T69I	-	-	Pseudomonas aeruginosa	aztreonam\|ofloxacin	Reslit	Candidate