Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mexR regulatory gene for efflux pump	V126E	GTT->GAA	mutations in regulators MexR, NalC, or NalD, reduced expression, increased efflux and resistance to certain beta-lactam antibiotics	Pseudomonas aeruginosa	fluoroquinolonesimipenemciprofloxacin+8 more	Reslit	Supported
mexR	Y3Ter	-	effux pump transcriptional repressor MexR	Pseudomonas aeruginosa	aztreonam avibactam\|carbapenems\|cephalosporins\|phenicols\|vaborbactam	Reference Gene Catalog	Established
mexS regulator of efflux pump	A155V	-	-	-	fluoroquinolones	Reslit	Candidate
mexS regulator of MexEF-OprN efflux pump	D249N	-	-	Pseudomonas aeruginosa	ciprofloxacinciprofloxacin\|norfloxacin\|imipenem\|meropenem	Reslit	Candidate
mexS regulator of the expression of mexEF-oprN	E87K	-	-	Pseudomonas aeruginosa	tobramycin\|aztreonam	Reslit	Candidate
mexS efflux pump regulator	G123R	-	-	Pseudomonas aeruginosa	imipenem\|relebactam	Reslit	Candidate
mexS transcriptional regulator of mexAB-oprM efflux pump	G195D	-	-	Pseudomonas aeruginosa	piperacillin tazobactam\|ceftazidime\|cefepime\|meropenem\|imipenem\|tobramycin\|ciprofloxacin	Reslit	Candidate
mexS regulator of MexEF-OprN efflux pump	G78S	-	-	-	ciprofloxacin	Reslit	Candidate
mexS	L136Q	-	-	-	meropenem	Reslit	Candidate
mexS	L409P	-	-	-	meropenem	Reslit	Candidate