Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mtrR mtrrpromotersize66bp	-	del-57A	-	Neisseria gonorrhoeae	penicillin\|tetracycline\|cephalosporins\|macrolides	ResFinder Database	Established
mtrR	-	G-131A	multidrug efflux system transcriptional repressor MtrR promoter region	Neisseria gonorrhoeae	azithromycin\|beta lactams\|tetracycline	Reference Gene Catalog	Established
mtrR transcriptional regulator	35del	-	-	-	azithromycin	Reslit	Candidate
mtrR repressor of the mtrCDE operon	A39T	G116A	reduced structural stability, reduced sensitivity to hydrophobic antimicrobials, overexpression of the MtrCDE efflux pump and an increase in the MIC of ESCs, single resistance variant, multidrug efflux system transcriptional repressor MtrR	Neisseria gonorrhoeae, Neisseria meningitidis	erythromycin\|azithromycin\|kanamycinmacrolides\|cephalosporins\|tetracycline\|penicillinciprofloxacin\|azithromycin\|spectinomycin+14 more	Card DatabaseReference Gene CatalogReslit	Confirmed
mtrR transcriptional repressor of the mtrCDE efflux pump	A39Y	G115A	-	-	erythromycin\|azithromycin\|penicillin	Reslit	Candidate
mtrR Transcriptional repressor	A40D	-	-	Neisseria gonorrhoeae	ciprofloxacin\|azithromycin\|spectinomycinazithromycinceftriaxone	Reslit	Supported
mtrR Mtr efflux pump repressor	A46T	-	associated with elevated MICs, repressor of the Mtr efflux pump	Neisseria cinerea, Neisseria subflava, Neisseria elongata, Neisseria canis	doxycycline	Reslit	Candidate
mtrR transcriptional repressor of the mtrCDE efflux system	A86T	-	loss of function of the repressor	Neisseria gonorrhoeae	azithromycin	Reslit	Candidate
mtrR Transcriptional repressor	D79N	-	-	Neisseria gonorrhoeae	ciprofloxacin\|azithromycin\|spectinomycinpenicillin\|tetracyclineceftriaxone+2 more	Reslit	Supported
mtrR Transcriptional repressor	E117K	-	-	Neisseria gonorrhoeae	ciprofloxacin\|azithromycin\|spectinomycin	Reslit	Candidate