Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mtrR repressor of the mtrCDE operon	E202G	-	-	Neisseria gonorrhoeae	erythromycin\|azithromycin\|kanamycin	Reslit	Candidate
mtrR Transcriptional repressor	F62L	-	-	Neisseria gonorrhoeae	ciprofloxacin\|azithromycin\|spectinomycin	Reslit	Candidate
mtrR transcriptional repressor of the mtrCDE efflux pump	G162A	-	-	Neisseria gonorrhoeae	azithromycin	Reslit	Candidate
mtrR transcriptional repressor	G45A	-	loss of DNA binding	Neisseria gonorrhoeae	macrolides	Reslit	Candidate
mtrR MtrR transcriptional repressor	G45D	-	disrupts the DNA-binding domain of the MtrR repressor, Over-expression of MtrCDE efflux pump resulting in increased efflux, overexpression of the MtrCDE efflux pump, overexpression of and increased efflux from the MtrCDE efflux pump, single resistance variant, multidrug efflux system transcriptional repressor MtrR	Neisseria gonorrhoeae	ceftriaxone\|cefiximemacrolides\|cephalosporins\|tetracycline\|penicillintetracycline\|phenicols+18 more	Card DatabaseReference Gene CatalogReslit	Confirmed
mtrR multiple transferable efflux pump repressor	G45S	-	multidrug efflux system transcriptional repressor MtrR	Neisseria subflava, N. subflava, Neisseria gonorrhoeae	ciprofloxacinmacrolides\|tetracycline\|phenicols\|sulfonamidesciprofloxacin\|zoliflodacin+1 more	Reference Gene CatalogReslit	Confirmed
mtrR transcriptional repressor	H105Y	C314T	-	Neisseria gonorrhoeae	tetracycline\|phenicolsciprofloxacin\|azithromycin\|spectinomycinceftriaxone+4 more	Reslit	Supported
mtrR transcriptional repressor	L33V	-	-	Neisseria gonorrhoeae	tetracycline\|phenicols	Reslit	Candidate
mtrR multidrug efflux system transcriptional repressor MtrR	M197I	-	-	Neisseria gonorrhoeae	ceftriaxoneazithromycin\|erythromycin	Reslit	Candidate
mtrR transcriptional repressor	R44A	-	loss of DNA binding	Neisseria gonorrhoeae	macrolides	Reslit	Candidate