Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
nalD repressor of efflux pump	T11N	-	mutations in regulators MexR, NalC, or NalD, regulator of the MexAB-OprM efflux pump, efflux system transcriptional repressor NalD	Pseudomonas aeruginosa	fluoroquinolones\|cephalosporins\|aminoglycosidesquinolones\|macrolides\|tetracycline\|phenicolsceftazidime+1 more	Reference Gene CatalogReslit	Confirmed
nalD efflux pump regulator	T11P	-	overexpression of MexAB-OprM efflux pump	Pseudomonas aeruginosa	cephalosporins\|aztreonam\|aztreonam avibactam	Reslit	Candidate
nalD	T158I	-	efflux system transcriptional repressor NalD	Pseudomonas aeruginosa	aztreonam\|carbapenems\|phenicols\|tetracycline\|vaborbactam	Reference Gene Catalog	Established
nalD NalD repressor	T158P	-	regulator of the MexAB-OprM efflux pump	Pseudomonas aeruginosa	ceftazidimeaztreonam	Reslit	Candidate
nalD efflux pump regulator	V456A	-	-	Pseudomonas aeruginosa	quinolones\|beta lactams	Reslit	Candidate
narK membrane transport	H472Y	-	-	Escherichia coli	aztreonam\|clavulanic acid	Reslit	Candidate
ndh nicotinamide dehydrogenase	-	G-70T	-	-	isoniazid	Reslit	Candidate
ndh	-	G910del	-	Mycobacterium tuberculosis	isoniazid\|ethionamide	Reslit	Candidate
ndh nicotinamide adenine dinucleotide hydrogenase	-	G911del	-	Mycobacterium tuberculosis	isoniazid	Reslit	Candidate
ndh	A115T	-	single resistance variant	Mycolicibacterium smegmatis	isoniazid	Card Database	Established