Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC type II topoisomerase	D80E	-	-	Escherichia coli	fluoroquinolones	Reslit	Candidate
parC topoisomerase IV subunit C	D81H	-	-	Staphylococcus agnetis, Staphylococcus saprophyticus	ciprofloxacin	Reslit	Candidate
parC DNA gyrase subunit A	D82N	-	single resistance variant	Mycoplasma genitalium, Mycoplasmoides genitalium	moxifloxacin	Card DatabaseReslit	Confirmed
parC DNA topoisomerase IV subunit	D83E	-	-	-	fluoroquinolones	Reslit	Candidate
parC DNA topoisomerase IV subunit A	D83G	-	-	Streptococcus pneumoniae	fluoroquinolonesciprofloxacin\|levofloxacinlevofloxacin+2 more	Reslit	Supported
parC	D83H	-	DNA topoisomerase IV subunit A ParC	Streptococcus pneumoniae	quinolones	Reference Gene Catalog	Established
parC topoisomerase IV subunit C	D83N	G247A G249A	-	Streptococcus pneumoniae, Haemophilus influenzae	moxifloxacin\|levofloxacin\|gemifloxacinfluoroquinolonesciprofloxacin\|levofloxacin+4 more	Reslit	Supported
parC topoisomerase IV subunit C	D83V	-	-	Streptococcus pyogenes	levofloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	D83Y	G247T G249T	-	Streptococcus pneumoniae, Streptococcus oralis, Streptococcus mitis	levofloxacinfluoroquinolonesciprofloxacin\|levofloxacin\|sparfloxacin\|trovafloxacin+2 more	Reslit	Supported
parC DNA topoisomerase IV subunit A	D84A	-	-	Staphylococcus epidermidis	ciprofloxacin\|ofloxacin\|gatifloxacin\|moxifloxacin	Reslit	Candidate