Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC DNA topoisomerase IV subunit A	D84C	-	-	Staphylococcus epidermidis	ciprofloxacin\|ofloxacin\|gatifloxacin\|moxifloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	D84G	-	-	Escherichia coli, Shigella sonnei, Mycoplasma genitalium, Staphylococcus epidermidis	levofloxacinciprofloxacin\|levofloxacin\|gatifloxacin\|gemifloxacin\|garenoxacinciprofloxacin+2 more	Reslit	Supported
parC DNA topoisomerase IV, subunit C	D84H	-	-	Streptococcus pneumoniae	fluoroquinolones	Reslit	Candidate
parC	D84N	-	confers resistance	Mycoplasma synoviae, Mycoplasma bovis, Mycoplasma hyopneumoniae, Mycoplasma agalactiae, Mycoplasma genitalium, Staphylococcus epidermidis	enrofloxacinenrofloxacin\|danofloxacin\|marbofloxacinfluoroquinolones+3 more	Reslit	Supported
parC DNA topoisomerase IV subunit C	D84V	-	-	Staphylococcus epidermidis	gatifloxacin\|moxifloxacin	Reslit	Candidate
parC DNA gyrase subunit C	D84Y	-	-	Mycoplasma genitalium, Staphylococcus epidermidis	fluoroquinolonesgatifloxacin\|moxifloxacin	Reslit	Supported
parC topoisomerase IV subunit A	D85G	-	-	Staphylococcus epidermidis	levofloxacin\|gatifloxacin\|moxifloxacin\|tosufloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	D85N	-	-	Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus pneumoniae	levofloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	D86G	-	DNA topoisomerase IV subunit A ParC	Neisseria gonorrhoeae	fluoroquinolonesquinolones	Reference Gene CatalogReslit	Confirmed
parC	D86H	-	single resistance variant	Streptococcus pneumoniae	fluoroquinolones	Card Database	Established