Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC DNA topoisomerase IV subunit	N542S	AAG->TCA	-	Mycoplasma hominis	ofloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	N638S	-	-	-	fluoroquinolones	Reslit	Candidate
parC DNA topoisomerase IV subunit	N828D	A2483G	-	Mycoplasma hominis	ofloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	N84D	-	-	-	enrofloxacin\|danofloxacin\|orbifloxacin	Reslit	Candidate
parC DNA topoisomerase IV ParC subunit	N91D	A273G	-	Streptococcus pneumoniae, Streptococcus oralis, Streptococcus mitis, Streptococcus dysgalactiae	ciprofloxacin\|levofloxacinlevofloxacinfluoroquinolones+2 more	Reslit	Supported
parC DNA topoisomerase IV subunit C	P105T	-	-	Pseudomonas aeruginosa	fluoroquinolonesciprofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	P116R	-	-	Pseudomonas aeruginosa	enrofloxacin\|marbofloxacin	Reslit	Candidate
parC DNA topoisomerase IV ParC subunit	P140S	-	-	Streptococcus dysgalactiae	levofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit A	P140T	-	-	Escherichia coli	fluoroquinolones	Reslit	Candidate
parC topoisomerase IV subunit ParC	P261T	-	-	Mycoplasma genitalium	ciprofloxacin\|garenoxacin\|moxifloxacin\|gatifloxacin\|sparfloxacin\|tosufloxacin\|levofloxacin\|fleroxacin\|norfloxacin\|clinafloxacin\|nadifloxacin\|pazufloxacin	Reslit	Candidate