Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC DNA topoisomerase IV subunit C	S87F	-	-	Neisseria gonorrhoeae	ciprofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	S87I	-	DNA topoisomerase IV subunit A ParC	Neisseria gonorrhoeae, Pseudomonas aeruginosa, Neisseria meningitidis, Providencia rettgeri, Providencia stuartii	ciprofloxacinciprofloxacin\|levofloxacinciprofloxacin\|garenoxacin\|sitafloxacin+3 more	Reference Gene CatalogReslit	Confirmed
parC topoisomerase IV	S87L	AGT->CTT T261C C262T	DNA topoisomerase IV subunit A ParC	Pseudomonas aeruginosa, Acinetobacter baumannii, Neisseria gonorrhoeae, Pseudomonas putida, Enterococcus faecalis, Enterococcus faecium, P. aeruginosa	ciprofloxacinfluoroquinoloneslevofloxacin+9 more	Reference Gene CatalogReslit	Confirmed
parC DNA topoisomerase IV subunit C	S87N	G260A	single resistance variant, DNA topoisomerase IV subunit A ParC	Pseudomonas aeruginosa, Neisseria gonorrhoeae, Neisseria meningitidis	ciprofloxacinciprofloxacin\|garenoxacin\|sitafloxacinfluoroquinolones+1 more	Card DatabaseReference Gene CatalogReslit	Confirmed
parC DNA topoisomerase IV subunit C	S87R	-	single resistance variant, DNA topoisomerase IV subunit A ParC	Neisseria gonorrhoeae, Neisseria meningitidis, Providencia rettgeri, Providencia stuartii	ciprofloxacinciprofloxacin\|levofloxacinfluoroquinolones+2 more	Card DatabaseReference Gene CatalogReslit	Confirmed
parC DNA topoisomerase IV subunit C	S87W	-	DNA topoisomerase IV subunit A ParC	Pseudomonas aeruginosa	ciprofloxacinfluoroquinoloneslevofloxacin\|ciprofloxacin+4 more	Reference Gene CatalogReslit	Confirmed
parC DNA topoisomerase IV subunit C	S88P	T263C	DNA topoisomerase IV subunit A ParC	Neisseria gonorrhoeae, Neisseria meningitidis	ciprofloxacinciprofloxacin\|levofloxacinciprofloxacin\|garenoxacin\|sitafloxacin+2 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
parC DNA gyrase subunit B	S89F	-	-	Mycoplasma amphoriforme	moxifloxacin\|levofloxacin	Reslit	Candidate
parC topoisomerase IV subunit A	S89I	-	-	Clostridium perfringens	ciprofloxacin\|norfloxacin\|gatifloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	S89L	-	-	-	quinolones	Reslit	Candidate