Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampC cephalosporinase	E114A	-	-	Pseudomonas aeruginosa	ceftazidime\|cefepime\|ticarcillin\|imipenem	Reslit	Candidate
ampC AmpC β-lactamase	E219K	-	enhanced cephalosporin resistance	Pseudomonas aeruginosa	ceftazidime\|ceftolozane	Reslit	Candidate
ampC beta-lactamase	E221K	-	-	Pseudomonas aeruginosa	ceftolozane tazobactam	Reslit	Candidate
ampC β-lactamase	E247G	-	-	Pseudomonas aeruginosa	ceftolozane	Reslit	Candidate
ampC beta-lactamase	E247K	-	reduced susceptibility to inhibition by avibactam	Pseudomonas aeruginosa	ceftolozane\|ceftazidimeavibactam\|tazobactamceftolozane+1 more	Reslit	Supported
ampC AmpC β-lactamase	F121L	-	enhanced cephalosporin resistance	Pseudomonas aeruginosa	ceftazidime\|ceftolozaneceftolozane tazobactam	Reslit	Candidate
ampC beta-lactamase	F147L	-	-	Pseudomonas aeruginosa	ceftolozane tazobactam\|ceftazidime avibactamceftolozane	Reslit	Candidate
ampC beta-lactamase	G123D	-	-	E. coli	amoxicillin	Reslit	Candidate
ampC beta-lactamase	G157D	-	-	Pseudomonas aeruginosa	ceftolozane tazobactam	Reslit	Candidate
ampC chromosome-encoded cephalosporinase	G183D	-	decreased hydrolytic activity toward TZP and carbapenems, reduced susceptibility to inhibition by avibactam	Pseudomonas aeruginosa	ceftolozane tazobactam\|ceftazidime avibactamceftolozane\|ceftazidimeavibactam+4 more	Reslit	Supported