Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| G423R | - | Target modification, DNA topoisomerase IV subunit B ParE | Escherichia coli | nalidixic acid|ciprofloxacinquinolones | Reference Gene CatalogResFinder Database | Confirmed | |
parE topoisomerase IV subunit E | G475K | - | - | Streptococcus pneumoniae | levofloxacin | Reslit | Candidate |
parE DNA topoisomerase IV subunit ParE | G486S | - | - | fluoroquinolones | Reslit | Candidate | |
| G78S | - | single resistance variant, DNA topoisomerase IV subunit B ParE | Staphylococcus aureus | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
parE topoisomerase IV subunit | H103Y | - | Streptococcus pneumoniae | moxifloxacin|sparfloxacin|grepafloxacin | Reslit | Candidate | |
parE topoisomerase IV subunit E | H212Y | - | - | Haemophilus haemolyticus | levofloxacin|tosufloxacin|moxifloxacin | Reslit | Candidate |
parE DNA topoisomerase IV subunit E | H221Y | - | - | Streptococcus agalactiae | levofloxacin | Reslit | Candidate |
| H462Y | - | Target modification, DNA topoisomerase IV subunit B ParE | Salmonella enterica | nalidixic acid|ciprofloxacinquinolones | Reference Gene CatalogResFinder Database | Confirmed | |
parE DNA topoisomerase IV subunit B | H518Y | - | - | - | enrofloxacin | Reslit | Candidate |
parE DNA topoisomerase IV subunit B | H59R | - | - | - | ciprofloxacin|levofloxacin | Reslit | Candidate |
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