Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ampC beta-lactamase | P217Q | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC Cephalosporin-hydrolyzing class C beta-lactamase | P58S | - | - | Enterobacter hormaechei | cefiderocol | Reslit | Candidate |
ampC cephalosporinase | Q155I | - | - | Pseudomonas aeruginosa | ceftazidime|cefepime|ticarcillin|imipenem | Reslit | Candidate |
ampC AmpC | Q86L | - | derepression of AmpC | Enterobacter cloacae | cefoxitin|cefotaxime|cefepime|ertapenem|imipenem|meropenem | Reslit | Candidate |
ampC β-lactamase | R148W | - | increased resistance to ceftazidime/avibactam and cefepime | Klebsiella aerogenes | ceftazidime avibactam|cefepime | Reslit | Candidate |
ampC beta-lactamase | S273R | - | - | Escherichia coli | cefoxitin | Reslit | Candidate |
ampC β-lactamase | S287C | - | increased resistance | E. coli | cefepime | Reslit | Candidate |
ampC β-lactamase | S287N | - | increased resistance | E. coli | cefepime | Reslit | Candidate |
ampC β-lactamase | S90A | - | The nonphosphorylatable mutant S90A was found to be more resistant to imipenem | Acinetobacter baumannii | imipenem | Reslit | Candidate |
ampC β-lactamase | S90D | - | The phosphorylation-simulated mutant S90D was sensitive to imipenem | Acinetobacter baumannii | imipenem | Reslit | Candidate |
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