Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ampC beta-lactamase | T105A | - | more efficient carbapenem and cefepime hydrolysis | Pseudomonas aeruginosa | imipenem|ceftazidime|cefepimeceftazidime|aztreonam | Reslit | Candidate |
ampC beta-lactamase | T70I | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC β-lactamase | T79A | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC beta-lactamase | T96I | - | reduced susceptibility to inhibition by avibactam | Pseudomonas aeruginosa | ceftolozane|ceftazidimeavibactamceftolozane+1 more | Reslit | Supported |
ampC β-lactamase | V179L | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC β-lactamase | V213A | - | increased β-lactamase hydrolysis activity | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC beta-lactamase | V239A | - | - | Pseudomonas aeruginosa | aztreonam | Reslit | Candidate |
ampC Cephalosporin-hydrolyzing class C beta-lactamase | V318A | - | - | Enterobacter hormaechei | cefiderocol | Reslit | Candidate |
ampC β-lactamase | V329I | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC cephalosporinase | V356I | - | - | Pseudomonas aeruginosa | ceftazidime|cefepime|ticarcillin|imipenempiperacillin tazobactam|ceftazidime | Reslit | Candidate |
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