Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
parE DNA topoisomerase IV subunit B | Q460P | - | - | Klebsiella pneumoniae | ciprofloxacin|levofloxacin|moxifloxacin | Reslit | Candidate |
parE topoisomerase IV subunit B | R135H | - | - | Ochrobactrum intermedium | quinolones | Reslit | Candidate |
| R136G | - | single resistance variant, DNA topoisomerase IV subunit B ParE | Staphylococcus aureus | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
parE DNA topoisomerase IV subunit B | R30C | - | - | - | ciprofloxacin|levofloxacin | Reslit | Candidate |
parE topoisomerase IV subunit E | R320S | - | - | Neisseria cinerea | ciprofloxacin | Reslit | Candidate |
parE DNA topoisomerase IV subunit B | R420H | - | - | - | enrofloxacin | Reslit | Candidate |
parE topoisomerase IV subunit B | R432S | - | - | Escherichia coli | ciprofloxacin | Reslit | Candidate |
parE topoisomerase IV subunit E | R444C | - | - | Staphylococcus aureus | nemonoxacin|moxifloxacin|levofloxacin|ciprofloxacin | Reslit | Candidate |
| R444S | - | DNA topoisomerase IV subunit B ParE | Staphylococcus aureus | quinolones | Reference Gene Catalog | Established | |
parE DNA topoisomerase IV subunit B | R447C | - | - | Streptococcus pneumoniae | levofloxacin | Reslit | Candidate |
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