Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pirA iron transport protein | M1A | - | - | - | cefiderocol | Reslit | Candidate |
pirA PirA ferric enterobactin receptor | Y636* | - | premature termination of the protein translation and alters the structure of the β-barrel | Pseudomonas aeruginosa | cefiderocol | Reslit | Candidate |
pitA transporter | - | - | Escherichia coli | gentamicin | Reslit | Candidate | |
pitA proline transporter | G123D | - | Staphylococcus aureus | daptomycin | Reslit | Candidate | |
| D304G | - | - | cefiderocol | Reslit | Candidate | ||
piuA siderophore uptake receptor | Q34H | - | - | Pseudomonas aeruginosa | cefiderocol | Reslit | Candidate |
piuA TonB-dependent receptor protein | Q38H | - | - | Pseudomonas aeruginosa | cefiderocol | Reslit | Candidate |
| Q548Ter | - | TonB-dependent siderophore receptor PiuA | Pseudomonas aeruginosa | cefiderocol|cephalosporins | Reference Gene Catalog | Established | |
piuC iron transport protein | M1V | - | - | Acinetobacter baumannii | cefiderocol | Reslit | Candidate |
piuC siderophore utilization | R201H | - | - | Pseudomonas aeruginosa, Acinetobacter spp. | cefiderocol | Reslit | Candidate |
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