Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrA two-component system sensor kinase	E106A	-	-	Escherichia coli	colistin	Reslit	Candidate
pmrA two-component system response regulator	E123D	-	predicted to affect the function of proteins encoded by these genes	Escherichia coli	colistin	Reslit	Candidate
pmrA two-component system regulator	E123K	-	-	-	colistin	Reslit	Candidate
pmrA transmembrane protein	E126K	-	-	E. coli	colistin	Reslit	Candidate
pmrA two-component system sensor kinase	E184D	-	-	Escherichia coli	colistin	Reslit	Candidate
pmrA response regulator	E218K	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrA Two-component system sensor histidine kinase	E8D	GAG->GAT	constitutive expression of pmrA that leads to the up-regulation of the pmrCAB operon, and subsequent synthesis and addition of PEtN to the 4′-phosphate or 1′-phosphate of lipid A, two-component system response regulator PmrA	Acinetobacter baumannii	colistin	Reference Gene CatalogReslit	Confirmed
pmrA two-component response regulator	G114D	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrA two-component system response regulator	G123D	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrA two-component system response regulator	G144S	-	-	Escherichia coli, E. coli	colistin	Reslit	Supported