Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB histidine kinase	L14S	-	Target modification, two-component system sensor histidine kinase PmrB	Salmonella enterica	polymyxin b\|colistinpolymyxinscolistin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
pmrB two-component system histidine kinase	L160F	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB	L167P	-	two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	colistin	Reference Gene Catalog	Established
pmrB	L168K	-	two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	colistin	Reference Gene Catalog	Established
pmrB sensor kinase of two-component system, PmrAB	L17P	-	confers resistance to colistin	Pseudomonas aeruginosa	colistin	Reslit	Candidate
pmrB	L17Q	-	two-component system sensor histidine kinase PmrB	Klebsiella pneumoniae, Pseudomonas aeruginosa	colistin	Reference Gene Catalog	Established
pmrB histidine kinase	L17R	-	predicted to affect the function of PmrB based on SIFT score (<0.05)	Escherichia coli	colistin	Reslit	Candidate
pmrB two-component system sensor kinase	L189Q	-	-	Pseudomonas aeruginosa	polymyxin b	Reslit	Candidate
pmrB sensor kinase of two-component system, PmrAB	L18P	-	confers resistance to colistin	Pseudomonas aeruginosa	colistin	Reslit	Candidate
pmrB two-component system histidine kinase	L206P	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate