Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB two-component system sensor kinase	L339C	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB histidine kinase	L344P	-	enhanced ATP binding affinity and protein stability	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB two-component system histidine kinase	L5S	-	-	Acinetobacter baumannii, Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB sensor kinase	L82R	-	two-component system sensor histidine kinase PmrB	Klebsiella pneumoniae	colistinpolymyxins	Reference Gene CatalogReslit	Confirmed
pmrB two-component system sensor kinase	L9P	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB histidine kinase	M12I	-	-	Acinetobacter baumannii	polymyxin b	Reslit	Candidate
pmrB two-component system histidine kinase	M145I	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB two-component regulatory system	M145K	-	disruption of pmrB leads to increased susceptibility to colistin	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB two-component system histidine kinase	M15T	-	-	Salmonella spp.	polymyxin b\|colistin	Reslit	Candidate
pmrB histidine kinase	M186I	-	Target modification, two-component system sensor histidine kinase PmrB	Salmonella enterica	polymyxin b\|colistincolistin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed