Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB sensor protein PmrB	M213L	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB two-component system sensor kinase	M285L	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB sensor kinase	M292I	-	gain-of-function	Pseudomonas aeruginosa	colistin	Reslit	Candidate
pmrB two-component response regulator	M292T	-	two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	polymyxin bcolistin	Reference Gene CatalogReslit	Confirmed
pmrB histidine kinase	M308R	-	associated with HR to colistin	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB two-component system histidine kinase	M308T	-	-	Acinetobacter baumannii, Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB regulatory protein involved in colistin resistance	M4I	G12C	-	E. coli	colistin	Reslit	Candidate
pmrB histidine kinase	N105K	-	-	Klebsiella pneumoniae	polymyxins	Reslit	Candidate
pmrB histidine kinase	N130Y	-	Target modification, two-component system sensor histidine kinase PmrB	Salmonella enterica	polymyxin b\|colistincolistin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
pmrB two-component system sensor kinase	N268Y	-	associated with TG resistance	Acinetobacter baumannii	colistin	Reslit	Candidate