Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pncA pyrazinamidase	D63H	-	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card DatabaseReslit	Confirmed
pncA	D63Y	-	multiple resistance variants, single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card Database	Established
pncA	D80H	-	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card Database	Established
pncA pyrazinamidase	D86G	-	-	Mycobacterium tuberculosis	pyrazinamide	Reslit	Candidate
pncA	D86V	-	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card Database	Established
pncA pyrazinamidase/nicotinamidase	D8A	GAT->GCA	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card DatabaseReslit	Confirmed
pncA pyrazinamidase	D8E	-	disrupts catalytic activity, single resistance variant	Mycobacterium tuberculosis, Mycobacterium bovis	pyrazinamide	Card DatabaseReslit	Confirmed
pncA pyrazinamidase/nicotinamidase	D8G	A25G	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card DatabaseReslit	Confirmed
pncA Pyrazinamidase	D8H	-	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card DatabaseReslit	Confirmed
pncA pyrazinamidase	D8L	-	disrupts catalytic activity	Mycobacterium tuberculosis, Mycobacterium bovis	pyrazinamide	Reslit	Candidate