Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
bceB transporter	S219F	-	no activity	Bacillus subtilis	bacitracin	Reslit	Candidate
bceB transporter	S542L	-	altered sensitivity	Bacillus subtilis	bacitracin	Reslit	Candidate
bceB transporter	V619M	-	low signal output	Bacillus subtilis	bacitracin	Reslit	Candidate
bdcA biofilm dispersal protein	G135S	-	-	E. coli, Escherichia coli	nalidixic acid\|norfloxacin\|ciprofloxacin\|levofloxacinnorfloxacin	Reslit	Candidate
betP betaine–carnitine–choline transporter (BCCT) family transporter	L314R	-	-	Mycobacterium tuberculosis	cycloserine	Reslit	Candidate
bioC O-methyltransferase	D75A	-	The D75A mutation disrupts SAM binding and reduces enzymatic activity, indicating a critical role in BioC function.	Acinetobacter baumannii, Klebsiella pneumoniae	polymyxins	Reslit	Candidate
bioC O-methyltransferase	E50A	-	The E50A mutation disrupts SAM binding and reduces enzymatic activity, indicating a critical role in BioC function.	Acinetobacter baumannii, Klebsiella pneumoniae	polymyxins	Reslit	Candidate
bioC O-methyltransferase	K194A	-	The K194A mutation affects the interaction with the ACP carrier, reducing enzymatic activity.	Acinetobacter baumannii, Klebsiella pneumoniae	polymyxins	Reslit	Candidate
bioC O-methyltransferase	K201A	-	The K201A mutation affects the interaction with the ACP carrier, reducing enzymatic activity.	Acinetobacter baumannii, Klebsiella pneumoniae	polymyxins	Reslit	Candidate
bioC O-methyltransferase	K215A	-	The K215A mutation affects the interaction with the ACP carrier, reducing enzymatic activity.	Acinetobacter baumannii, Klebsiella pneumoniae	polymyxins	Reslit	Candidate