Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	S485L	-	-	Escherichia coli, Salmonella enterica	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S485P	-	-	Clostridioides difficile	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S486F	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus epidermidis	rifampicin	Reference Gene CatalogReslit	Confirmed
rpoB RNA polymerase beta subunit	S486L	T1457C	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus, Staphylococcus pseudintermedius	rifampicinteicoplanin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	S486Y	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus epidermidis	rifampicin	Reference Gene CatalogReslit	Confirmed
rpoB RNA polymerase beta subunit	S487C	-	-	Staphylococcus epidermidis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S487F	-	-	Staphylococcus epidermidis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	S487L	T1459C	single resistance variant	Staphylococcus aureus, Bacillus subtilis	rifampicincefotaxime\|rifampicin	Card DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	S487Y	-	-	Staphylococcus epidermidis	rifampicin	Reslit	Candidate
rpoB	S488P	-	single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Clostridium ljungdahlii, Clostridioides difficile	rifampicinrifamycins	Card DatabaseReference Gene Catalog	Confirmed