Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
blaROB-1 β-lactamase	A237T	-	increased resistance to extended-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations	Escherichia coli	cefotaxime\|amoxicillin clavulanic acid	Reslit	Candidate
blaROB-1 β-lactamase	L169S	-	increased resistance to extended-spectrum cephalosporins	Escherichia coli	cefotaxime	Reslit	Candidate
blaROB-1 β-lactamase	R164W	-	increased resistance to extended-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations	Escherichia coli	cefotaxime\|amoxicillin clavulanic acid	Reslit	Candidate
blaSHV-1 beta-lactamase	-	A2C	-	Klebsiella pneumoniae	ceftazidime\|piperacillin tazobactam	Reslit	Candidate
blaSHV-1 beta-lactamase	D104K	-	-	Escherichia coli	cefotaxime\|ceftazidime	Reslit	Candidate
blaSHV-1 beta-lactamase	D104R	-	-	Escherichia coli	cefotaxime\|ceftazidime	Reslit	Candidate
blaSHV-1 beta-lactamase	G238A	-	conferred the most resistance to penicillins and cephalosporins	Escherichia coli	penicillin\|cephalosporins	Reslit	Candidate
blaSHV-1 beta-lactamase	G238C	-	demonstrated lower levels of resistance	Escherichia coli	penicillin\|cephalosporins	Reslit	Candidate
blaSHV-1 beta-lactamase	G238D	-	demonstrated lower levels of resistance	Escherichia coli	penicillin\|cephalosporins	Reslit	Candidate
blaSHV-1 beta-lactamase	G238P	-	demonstrated lower levels of resistance	Escherichia coli	penicillin\|cephalosporins	Reslit	Candidate