Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
blaPDC β-lactamase	N320S	A958G	enhanced catalytic efficiency	Pseudomonas aeruginosa	ceftazidime\|ceftolozaneceftazidime\|ceftolozane\|aztreonam\|piperacillin	Reslit	Candidate
blaPDC β-lactamase	P153L	-	enhanced catalytic efficiency	Pseudomonas aeruginosa	ceftazidime\|ceftolozane\|aztreonam\|piperacillin	Reslit	Candidate
blaPDC β-lactamase	Q120K	C360A	enhanced catalytic efficiency	Pseudomonas aeruginosa	ceftazidime\|ceftolozaneceftazidime\|ceftolozane\|aztreonam\|piperacillin	Reslit	Candidate
blaPDC β-lactamase	T255P	A764C	-	-	ceftazidime\|ceftolozane	Reslit	Candidate
blaPDC β-lactamase	V211A	G631C	enhanced catalytic efficiency	Pseudomonas aeruginosa	ceftazidime\|ceftolozaneceftazidime\|ceftolozane\|aztreonam\|piperacillin	Reslit	Candidate
blaPenA β-lactamase	P167S	-	-	-	carbapenems	Reslit	Candidate
blaPenI β-lactamase	C69Y	-	-	Escherichia coli, Burkholderia pseudomallei	ceftazidime	Reslit	Candidate
blaPenI β-lactamase	P167S	-	-	Escherichia coli, Burkholderia pseudomallei	ceftazidime	Reslit	Candidate
blaPER-4 beta-lactamase	-	G360C	reduced avibactam affinity and high-level CZA resistance	Pseudomonas aeruginosa	ceftazidime\|ceftazidime avibactam	Reslit	Candidate
blaPER Extended-spectrum beta-lactamase	S164F	-	-	-	cephalosporins	Reslit	Candidate