Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	D89V	-	single resistance variant	Mycobacterium tuberculosis	fluoroquinolones	Card Database	Established
gyrA	D90A	-	Target modification, DNA gyrase subunit A GyrA	Mycobacterium tuberculosis, Campylobacter jejuni, Campylobacter coli	levofloxacin\|moxifloxacinnalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D90G	-	single resistance variant	Mycobacterium tuberculosis, Bartonella bacilliformis	ofloxacin\|moxifloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D90N	G269A	mutations in the DNA gyrase A (GyrA) region at multiple positions, Target modification, DNA gyrase subunit A GyrA	Campylobacter jejuni, Mycobacterium tuberculosis, Campylobacter coli	ciprofloxacin\|nalidixic acidquinolonesofloxacin+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	D90T	-	Target modification, DNA gyrase subunit A GyrA	Campylobacter jejuni, Campylobacter coli	nalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA DNA gyrase subunit A	D90Y	G269C	DNA gyrase subunit A GyrA	Campylobacter jejuni, Campylobacter coli	ciprofloxacin\|nalidixic acidfluoroquinolonesquinolones	Reference Gene CatalogReslit	Confirmed
gyrA DNA gyrase subunit A	D91A	-	-	Corynebacterium spp., Corynebacterium urealyticum, Helicobacter pylori	fluoroquinolonesciprofloxacin\|levofloxacin\|moxifloxacinlevofloxacin	Reslit	Supported
gyrA DNA gyrase subunit A	D91G	G273C	single resistance variant, multiple resistance variants, DNA gyrase subunit A GyrA	Helicobacter pylori, Corynebacterium spp.	levofloxacin\|moxifloxacin\|ciprofloxacinlevofloxacinfluoroquinolones+2 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase A	D91H	-	single resistance variant	Helicobacter pylori	levofloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D91N	G272A G273A	multiple resistance variants, single resistance variant, DNA gyrase subunit A GyrA	Helicobacter pylori, Campylobacter fetus	levofloxacin\|moxifloxacin\|ciprofloxacinlevofloxacinfluoroquinolones+3 more	Card DatabaseReference Gene CatalogReslit	Confirmed