Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	G81S	-	Target modification, DNA gyrase subunit A GyrA	Acinetobacter baumannii, Salmonella enterica	ciprofloxacin\|levofloxacinnalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	G82C	-	DNA gyrase subunit A GyrA	Staphylococcus aureus	quinolones	Reference Gene Catalog	Established
gyrA DNA gyrase subunit A	G82D	-	-	E. coli	norfloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G83D	-	-	Pseudomonas aeruginosa, Salmonella Paratyphi, Escherichia coli	fluoroquinolonesciprofloxacin	Reslit	Supported
gyrA DNA gyrase subunit A	G83F	-	-	Klebsiella pneumoniae	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	G83I	-	-	Klebsiella pneumoniae	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	G83R	G248C	-	Pseudomonas aeruginosa	ciprofloxacin\|nalidixic acidciprofloxacin\|levofloxacinciprofloxacin+1 more	Reslit	Supported
gyrA DNA gyrase subunit A	G83S	-	disruption of the water-magnesium ion bridge	Escherichia coli	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G84R	-	-	Streptococcus pneumoniae	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G85A	-	-	-	levofloxacin	Reslit	Candidate