Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	G85C	-	single resistance variant	Helicobacter pylori	levofloxacin\|moxifloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	G87D	-	disruption of the water-magnesium ion bridge	Escherichia coli	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G87G	-	-	Klebsiella pneumoniae	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	G87N	-	-	Klebsiella pneumoniae	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	G882S	-	-	Acinetobacter baumannii	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	G88A	-	single resistance variant	Mycobacterium tuberculosis	fluoroquinolonesmoxifloxacin\|levofloxacinofloxacin+1 more	Card DatabaseResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	G88C	GGA->TGA G263T	single resistance variant	Mycobacterium smegmatis, Mycobacterium tuberculosis	ciprofloxacin\|levofloxacin\|moxifloxacin\|gatifloxacinlevofloxacin\|moxifloxacinfluoroquinolones+7 more	Card DatabaseResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	G88D	-	-	Mycobacterium aurum	levofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G88R	-	-	Mycobacterium tuberculosis	ofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G89A	-	-	Mycobacterium leprae	ofloxacin	Reslit	Candidate