Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
acrB Multidrug efflux pump RND permease	V139F	-	-	E. coli	tetracycline	Reslit	Candidate
acrB efflux pump component	V292A	-	-	Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa	delafloxacin\|gepotidacin\|omadacycline	Reslit	Candidate
acrB multidrug efflux transporter	V341A	-	resistance to fusidic acid and β-lactams	Escherichia coli	fusidic acid	Reslit	Candidate
acrB efflux pump component	V348I	-	-	Escherichia coli	tetracycline	Reslit	Candidate
acrB efflux pump component	V448E	-	reduces efflux pump activity	Klebsiella pneumoniae	fluoroquinolones	Reslit	Candidate
acrB RND multidrug efflux pump	V612F	-	increases resistance to linezolid, chloramphenicol, tetracycline, and fluoroquinolones, but decreases resistance to macrolides, increased resistance to tetracycline, fluoroquinolone, and linezolid, but reduced resistance to macrolides	E. coli, Klebsiella pneumoniae, Burkholderia pseudomallei	linezolid\|phenicols\|tetracycline\|fluoroquinolonestetracycline\|fluoroquinolones	Reslit	Candidate
acrE iterative type I PKS	-	C-145T	-	-	-	Reslit	Candidate
acrE	-	T-163A	-	-	-	Reslit	Candidate
acrE tailoring enzyme	-	T-204A	-	-	-	Reslit	Candidate
acrE	-	T-240C	-	-	-	Reslit	Candidate