Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	S79R	-	-	-	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S79Y	-	-	-	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase A	S80F	TCT -> TTC	-	Staphylococcus epidermidis, Staphylococcus coagulans, S. epidermidis	ciprofloxacin\|ofloxacin\|gatifloxacin\|moxifloxacinlevofloxacinenrofloxacin\|ciprofloxacin\|moxifloxacin+2 more	Reslit	Supported
gyrA DNA gyrase subunit A	S80I	TCA->ATA	confers resistance to fluoroquinolones, harbored mutations gyrA (S83F), gyrA (D87Y), and parC (S80I) associated with resistance to quinolones	Escherichia coli, Salmonella enterica	enrofloxacinfluoroquinolonesciprofloxacin\|nalidixic acid\|norfloxacin\|ofloxacin+2 more	Reslit	Supported
gyrA DNA gyrase subunit A	S80L	-	-	Staphylococcus aureus	moxifloxacinciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S80R	-	-	Salmonella enterica, Escherichia coli	ciprofloxacinfluoroquinolones	Reslit	Candidate
gyrA DNA gyrase A	S80Y	-	-	Staphylococcus epidermidis	ciprofloxacin\|ofloxacin\|gatifloxacin\|moxifloxacinlevofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S81A	-	-	Streptococcus pneumoniae	moxifloxacin\|levofloxacin\|gemifloxacinfluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	S81F	AGT -> TTC AGT->TTT GCA->TTA C244T G242T T243C	confers resistance, resistance	Streptococcus pneumoniae, Staphylococcus aureus, Streptococcus dysgalactiae, Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus suis	clinafloxacin\|ciprofloxacin\|trovafloxacinlevofloxacin\|clinafloxacinlevofloxacin+18 more	Reslit	Supported
gyrA DNA gyrase subunit	S81I	-	-	Streptococcus pneumoniae	ciprofloxacin\|levofloxacin\|moxifloxacin\|gatifloxacin\|gemifloxacin\|garenoxacin\|norfloxacin	Reslit	Candidate