Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	S91L	GCT->TTT	-	Acinetobacter baumannii, Neisseria gonorrhoeae	ciprofloxacinfluoroquinolones	Reslit	Supported
gyrA DNA gyrase subunit A	S91N	-	confers resistance to ciprofloxacin	Neisseria canis	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S91P	TCA->CCA T272C AGT->CCC T271C	alter the protein at codons 91, where serine was replaced with proline, single resistance variant	Mycobacterium tuberculosis, Mycobacterium smegmatis	fluoroquinolonesofloxacinciprofloxacin\|levofloxacin+15 more	Card DatabaseResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	S91R	-	confers resistance to ciprofloxacin	Neisseria canis, Tsukamurella	ciprofloxacinlevofloxacin\|ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase A subunit	S91T	-	-	Neisseria gonorrhoeae, Neisseria meningitidis, Neisseria lactamica, Neisseria subflava, Neisseria flavescens, Neisseria cinerea, Neisseria elongata, Neisseria mucosa, Neisseria sicca, Mycobacterium tuberculosis	ciprofloxacinofloxacinfluoroquinolones	Reslit	Supported
gyrA DNA gyrase A subunit	S91Y	-	DNA gyrase subunit A GyrA	Neisseria gonorrhoeae	ciprofloxacindelafloxacinfluoroquinolones+1 more	Reference Gene CatalogReslit	Confirmed
gyrA DNA gyrase subunit A	S94A	-	-	-	ofloxacinfluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	S94L	-	-	-	fluoroquinolonesofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S94P	-	-	Mycobacterium tuberculosis	levofloxacin\|moxifloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S95A	A283G	-	Mycobacterium tuberculosis	levofloxacin\|moxifloxacinofloxacin\|moxifloxacin	Reslit	Candidate