Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	T59I	ACG->ATA	-	Citrobacter freundii, Citrobacter braakii, Citrobacter youngae	nalidixic acid\|ciprofloxacin\|levofloxacin\|norfloxacinnalidixic acid\|ciprofloxacin\|levofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	T665S	-	increased resistance to FQs	Campylobacter jejuni	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase A subunit	T678A	-	-	Staphylococcus pseudintermedius	enrofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	T700N	-	-	-	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	T72C	-	-	-	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	T80A	-	single resistance variant	Mycobacterium tuberculosis	fluoroquinolonesquinolones	Card DatabaseResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	T80I	A240G	decreased affinity for ciprofloxacin	Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Campylobacter, Neisseria gonorrhoeae, Neisseria meningitidis	fluoroquinolonesciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	T81I	T242A	-	Campylobacter jejuni, Campylobacter coli, Streptococcus pneumoniae	quinoloneslevofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	T828N	-	-	-	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	T829A	-	-	-	fluoroquinolones	Reslit	Candidate